Purpose

The purpose of this study was to describe the elastic properties of the medial rectus muscle and optic nerve in Graves’ patients without clinically apparent ophthalmopathy using strain elastography (SE) and shear wave elastography (SWE) and to determine whether these elastic properties could be used to aid in the diagnosis of the medial rectus muscle or optic nerve involvement.

Materials and methods

Thirty participants diagnosed with Graves’ disease without ophthalmopathy and 30 healthy volunteers (control group) were prospectively examined between November 2018 and August 2019. SE and SWE findings in both groups were compared using the χ² test and the independent samples t test.

Results

A statistically significant softening of the medial rectus muscle was observed in the SE patterns of the Graves’ patients (p = 0.009). A statistically appreciable distinction was observed between the medial rectus muscle (7.64 ± 2.1 and 9.20 ± 1.7 kPa, p = 0.000) and the optic nerve (8.35 ± 2.8 and 9.37 ± 1.5 kPa, p = 0.019) in the SWE modulus of the Graves’ patients and healthy volunteers.

Conclusion

SE and SWE can be used to identify structural alterations to the medial rectus muscle and optic nerve before clinically apparent Graves’ ophthalmopathy has developed.

中文翻译：

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利用应变和剪切波弹性成像技术评估Graves患者的内侧直肌和视神经。

目的

这项研究的目的是使用应变弹性成像（SE）和剪切波弹性成像（SWE）描述没有临床上明显眼病的Graves患者的内侧直肌和视神经的弹性，并确定是否可以使用这些弹性。有助于诊断内直肌或视神经受累。

材料和方法

三十诊断患有格雷夫斯病参与者没有眼病及30名健康志愿者（对照组）2018年11月和2019年八月之间进行前瞻性研究SE和两组SWE发现使用比较χ ²检验和独立样本吨试验。

结果

在Graves患者的SE模式中，观察到内侧直肌的统计学显着软化（p  = 0.009）。 Graves的SWE模量在内侧直肌（7.64±2.1和9.20±1.7 kPa，p  = 0.000）和视神经（8.35±2.8和9.37±1.5 kPa，p = 0.019）之间观察到统计学上显着的区别患者和健康志愿者。

结论

SE和SWE可用于在临床上出现明显的Graves眼病之前识别内侧直肌和视神经的结构改变。