Porous organic frameworks (POFs) with a heteroatom rich ionic backbone have emerged as advanced materials for catalysis, molecular separation, and antimicrobial applications. The loading of metal ions further enhances Lewis acidity, augmenting the activity associated with such frameworks. Metal-loaded ionic POFs, however, often suffer from physicochemical instability, thereby limiting their scope for diverse applications. Herein, we report the fabrication of triaminoguanidinium-based ionic POFs through Schiff base condensation in a cost-effective and scalable manner. The resultant N-rich ionic frameworks facilitate selective CO₂ uptake and afford high metal (Zn(II): 47.2%) loading capacity. Owing to the ionic guanidinium core and ZnO infused mesoporous frameworks, Zn/POFs showed pronounced catalytic activity in the cycloaddition of CO₂ and epoxides into cyclic organic carbonates under solvent-free conditions with high catalyst recyclability. The synergistic effect of infused ZnO and cationic triaminoguanidinium frameworks in Zn/POFs led to robust antibacterial (Gram-positive, Staphylococcus aureus and Gram-negative, Escherichia coli) and antiviral activity targeting HIV-1 and VSV-G enveloped lentiviral particles. We thus present triaminoguanidinium-based POFs and Zn/POFs as a new class of multifunctional materials for environmental remediation and biomedical applications.

中文翻译：

---

多功能离子多孔框架，用于二氧化碳转化和抵抗微生物

具有富杂原子的离子主链的多孔有机骨架（POF）已作为催化，分子分离和抗菌应用的先进材料而出现。金属离子的负载进一步增强了路易斯酸度，增强了与此类骨架相关的活性。然而，金属负载的离子POF经常遭受物理化学的不稳定性，从而限制了其在各种应用中的范围。在本文中，我们报告了通过Schiff碱缩合以经济高效且可扩展的方式制备基于三氨基胍鎓的离子POF。所得的富氮离子骨架有助于选择性吸收CO ₂并提供高金属（Zn（II）：47.2％）的装载量。由于离子胍基核和注入ZnO的中孔骨架，Zn / POF在无溶剂条件下以高催化剂可回收性在CO ₂和环氧化物成环有机碳酸酯的环加成反应中显示出明显的催化活性。在Zn / POF中注入ZnO和阳离子三氨基胍盐骨架的协同作用导致了强大的抗菌作用（革兰氏阳性，金黄色葡萄球菌和革兰氏阴性，大肠杆菌）以及针对HIV-1和VSV-G包裹的慢病毒颗粒的抗病毒活性。因此，我们提出了基于三氨基胍的POF和Zn / POF，作为用于环境修复和生物医学应用的一类新型多功能材料。