Abstract

The present study was designed to indicate the protective effects of curcumin on dyslipidemia. Main databases were searched to recognise randomised clinical trials evaluating the effect of curcumin on blood lipid profiles. The pooled odds ratio with a 95% confidence interval (CI) was used to evaluate the effect of curcumin on blood lipid parameters. HDL-C levels in the curcumin group were 0.04-fold lower than placebo (95% CI:−0.36–0.29; Z = 0.23; p = .82). LDL-C levels in the curcumin group reduced by 0.17 versus the placebo group (95% CI: −0.43–0.09; Z = 1.27; p = .2). TC levels in the curcumin group were 0.21 lower versus the placebo group (95% CI: −0.55–0.13; Z = 1.22; p = .22). TG level in the curcumin group were 0.05 lower versus the placebo (95% CI: −0.20–0.11; Z = 0.58; p = .56). This study suggests that curcumin may reduce blood lipid levels and can be used as a hypolipidemic agent.

摘要

本研究旨在表明姜黄素对血脂异常的保护作用。搜索主要数据库以识别评估姜黄素对血脂谱影响的随机临床试验。具有 95% 置信区间 (CI) 的汇总优势比用于评估姜黄素对血脂参数的影响。姜黄素组的 HDL-C 水平比安慰剂组低 0.04 倍（95% CI：-0.36–0.29；Z =  0.23；p  = .82）。与安慰剂组相比，姜黄素组的 LDL-C 水平降低了 0.17（95% CI：-0.43–0.09；Z =  1.27；p  = .2）。姜黄素组的 TC 水平比安慰剂组低 0.21（95% CI：-0.55-0.13；Z =  1.22；p = .22)。姜黄素组的 TG 水平比安慰剂组低 0.05（95% CI：-0.20–0.11；Z =  0.58；p  = .56）。这项研究表明姜黄素可以降低血脂水平，并可用作降血脂剂。