Au nanoparticles were decorated on Ni-based metal–organic frameworks to improve their electrochemical performance for nonenzymatic glucose detection through a convenient and fast microwave-assisted process. Various techniques including scanning electron microscopy, transmission electron microscopy, X-ray diffraction, energy dispersive X-ray mapping and X-ray photoelectron spectroscopy were used to characterize the Au@Ni-BTC composites. The results revealed that Au nanoparticles were uniformly deposited on the Ni-BTC microspheres. The constructed Au@Ni-BTC sensors showed highly increased glucose detection performance with a wide linear range (5–7400 μM), high sensitivity (1447.1 μA mM⁻¹ cm⁻²) and low detection limit (1.5 μM). Moreover, they also exhibited good selectivity and preferable feasibility for serum sample analysis. The improved glucose sensing performance may be due to the synergistic effects of Au nanoparticles and Ni-BTC, which facilitated faster charge transfer in the electrochemical process. The study of Au@Ni-BTC may also provide a promising material for constructing highly efficient nonenzymatic glucose sensors.

金纳米颗粒在镍基金属-有机骨架上进行修饰，以通过便捷，快速的微波辅助过程提高其非酶法葡萄糖检测的电化学性能。Au @ Ni-BTC复合材料的特征包括扫描电子显微镜，透射电子显微镜，X射线衍射，能量色散X射线作图和X射线光电子能谱。结果表明，金纳米颗粒均匀沉积在Ni-BTC微球上。构造的Au @ Ni-BTC传感器在宽线性范围（5–7400μM）和高灵敏度（1447.1μAmM ^-1  cm ^-2）的情况下显示出大大提高的葡萄糖检测性能）和低检测限（1.5μM）。而且，它们还表现出良好的选择性和血清样品分析的优选可行性。改善的葡萄糖感测性能可能归因于Au纳米颗粒和Ni-BTC的协同作用，从而促进了电化学过程中更快的电荷转移。Au @ Ni-BTC的研究也可能为构建高效的非酶葡萄糖传感器提供有前途的材料。