In green approaches for electrocatalyst synthesis, sonochemical methods play a powerful role in delivering the abundant surface areas and nano-crystalline properties that are advantageous to electrocatalytic detection. In this article, we proposed the sphere-like and perovskite type of bimetal oxides which are synthesized through an uncomplicated sonochemical procedure. As a yield, the novel calcium titanate (orthorhombic nature) nanoparticles (CaTiO₃ NPs) decorated graphene oxide sheets (GOS) were obtained through simple ultrasonic irradiation by a high-intensity ultrasonic probe (Titanium horn; 50 kHz and 60 W). The GOS/CaTiO₃ NC were characterized morphologically and chemically through the analytical methods (SEM, XRD, and EDS). Besides, as-prepared nanocomposites were modified on a GCE (glassy carbon electrode) and applied towards electrocatalytic and electrochemical sensing of chemotherapeutic drug flutamide (FD). Notably, FD is a crucial anticancer drug and also a non-steroidal anti-androgen chemical. Mainly, the designed and modified sensor has shown a wide linear range (0.015–1184 µM). A limit of detection was calculated as nanomolar level (5.7 nM) and sensitivity of the electrode is 1.073 μA μM⁻¹ cm⁻². The GOS/CaTiO₃ modified electrodes have been tested in human blood and urine samples towards anticancer drug detection.

在用于电催化剂合成的绿色方法中，声化学方法在提供有利于电催化检测的丰富表面积和纳米晶体特性方面发挥着重要作用。在本文中，我们提出了通过简单的声化学方法合成的球形和钙钛矿型双金属氧化物。作为产率，通过高强度超声探头（钛喇叭； 50 kHz和60 W）通过简单的超声辐照获得了新型的钛酸钙（正交晶质）纳米颗粒（CaTiO ₃ NPs）装饰的氧化石墨烯片（GOS）。GOS / CaTiO ₃通过分析方法（SEM，XRD和EDS）对NC进行了形态和化学表征。此外，将制得的纳米复合材料在GCE（玻碳电极）上进行修饰，并应用于化学治疗药物氟他胺（FD）的电催化和电化学传感。值得注意的是，FD是重要的抗癌药，也是非甾体类抗雄激素化学物质。主要是，经过设计和修改的传感器显示出很宽的线性范围（0.015-1184 µM）。检测极限被计算为纳摩尔水平（5.7nM），并且电极的灵敏度为1.073μAμM ^-1  cm ^-2。GOS / CaTiO ₃修饰电极已在人体血液和尿液样本中进行了抗癌药物检测测试。