Abstract As for the SARS coronavirus in the 2003 epidemic, the presence of SARS-CoV-2 has been demonstrated in faeces and, in some cases, urine of infected people, as well as in wastewater. This paper proposes a critical review of the state of the art regarding studies on the presence of SARS-CoV-2 in wastewater and sewage sludge, the factors affecting its inactivation and the main proposed treatments. In-vitro tests demonstrated low resistance of SARS-CoV-2 to high temperature, while even significant changes in pH would not seem to determine the disappearance of the virus. In wastewater and in sewage sludge, to date studies on the influence of the different parameters on the inactivation of SARS-CoV-2 in real matrices are not available. Therefore, studies involving other HCoVs such as SARS-CoV and HCoV-229E have been also considered, in order to formulate a hypothesis regarding its behaviour in sewage and throughout the steps of biological treatments in WWTPs. Finally, SARS-CoV-2 in wastewater might track the epidemic trends: although being extremely promising, an effective and wide application of this approach requires a deeper knowledge of the amounts of viruses excreted through the faeces and the actual detectability of viral RNA in sewage.

中文翻译：

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下水道系统和连接设施中的 SARS-CoV-2

摘要 对于 2003 年流行的 SARS 冠状病毒，SARS-CoV-2 已在感染者的粪便和某些情况下的尿液以及废水中得到证实。本文对有关废水和污水污泥中 SARS-CoV-2 存在、影响其灭活的因素和主要拟议处理方法的研究现状进行了批判性回顾。体外测试表明 SARS-CoV-2 对高温的抵抗力较低，而即使 pH 值发生显着变化似乎也无法确定病毒是否消失。在废水和污水污泥中，迄今为止还没有关于不同参数对真实基质中 SARS-CoV-2 灭活的影响的研究。因此，还考虑了涉及其他 HCoV 的研究，例如 SARS-CoV 和 HCoV-229E，为了制定关于其在污水中和整个污水处理厂生物处理步骤中的行为的假设。最后，废水中的 SARS-CoV-2 可能会追踪流行趋势：尽管这种方法非常有前途，但有效和广泛的应用需要更深入地了解通过粪便排出的病毒数量以及污水中病毒 RNA 的实际检测能力.