The manufacture of sensors using large-scale production techniques, such as roll-to-roll (R2R) processing, may fulfill requirements of low-cost disposable devices. Herein, we report the fabrication of fully-printed electrochemical sensors using screen-printed carbon electrodes coated with carbon black inks through slot-die coating within an R2R process. As a proof of concept, sensors were produced to detect the neurotransmitter dopamine with high reproducibility and low limit of detection (0.09 μmol L⁻¹). Furthermore, fully-printed biosensors made with a tyrosinase-containing ink were used to detect catechol in natural water samples. Since slot-die deposition enables printing enzymes without significant activity loss, the biosensors exhibited high stability over a period of several weeks. Even more important, R2R slot-die coating may be extended to any type of sensors and biosensors with the possibility of large-scale manufacturing.

使用大规模生产技术（例如卷对卷（R2R）处理）的传感器制造可以满足低成本一次性设备的要求。在本文中，我们报告了在R2R工艺中使用通过缝隙模头涂层涂有炭黑墨水的丝网印刷碳电极制造的全印刷电化学传感器的过程。作为概念证明，生产了传感器以高重复性和低检测限（0.09μmolL ^-1）检测神经递质多巴胺。）。此外，用含酪氨酸酶的油墨制成的全印生物传感器用于检测天然水样品中的儿茶酚。由于狭缝模头沉积使印刷酶没有明显的活性损失，因此生物传感器在数周的时间内显示出高稳定性。更重要的是，R2R狭缝模具涂层可以扩展到任何类型的传感器和生物传感器，并具有大规模生产的可能性。