The nature of interaction of amino acid with drug are examined from the experimentally measured values of densities, ρ and ultrasonic speeds, u of l-arginine and l-histidine in aqueous-gentamicin sulphate (1% and 2% gentamicin sulphate in water, w/w) solvents over the temperature range from 293.15 K to 318.15 K and at atmospheric pressure. From the experimental ρ values, the apparent molar volume, V_ϕ, limiting apparent molar volume, V_ϕ^°, transfer volume, V_{ϕ, tr}^°, and limiting partial molar expansivity, E_ϕ^° were obtained. Using the u data, acoustic parameters, viz., apparent molar compressibility, K_{s, ϕ}, limiting apparent molar compressibility, K_{s, ϕ}^° and transfer compressibility, K_{s, ϕ, tr}^° have been evaluated. The results have been interpreted in terms of possible solute-solute and solute-solvent interactions.

与药物氨基酸的相互作用的性质，从密度的实验测量值检查ρ和超声波速度，ü的升精氨酸和升在含水硫酸庆大霉素（1％和2％硫酸庆大霉素水溶液组氨酸，瓦特/ w）溶剂，温度范围为293.15 K至318.15 K，且在大气压下。根据实验ρ值，表观摩尔体积V _ϕ，极限表观摩尔体积V _ϕ ^°，转移体积V _ϕ，tr ^°和极限部分摩尔膨胀率E _ϕ获得^°。使用u数据，声学参数，即。，表观摩尔压缩率K _s，ϕ，极限表观摩尔压缩率K _s，ϕ ^°和传递压缩率K _s，ϕ，tr ^°进行了评估。已根据可能的溶质-溶质和溶质-溶剂相互作用来解释结果。