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Polyradiculitis in autoimmune encephalitis: a case report and review
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Pub Date : 2020-07-02 , DOI: 10.1186/s41983-020-00192-1
Tejas R. Mehta , Elanagan Nagarajan

Background Limbic encephalitis is a subacute progressive disorder characterized by disturbances in memory and behavior along with seizures. Antibodies against leucine-rich glioma-inactivated 1 (LGI1) are associated with a subtype of encephalitis which along with the abovementioned symptoms is also characterized by severe pain and autonomic dysfunction. The classical radiological presentation of LGI1 encephalitis is that of amygdala and hippocampal enlargement unilaterally or bilaterally with a T2 hyperintensity. Extratemporal involvement is considered a rare feature. Case description We present the only known case in our knowledge of anti-LGI1 encephalitis in a 47-year-old male presenting as dorsal root ganglia and spinal nerve enhancement on imaging. Discussion Clinicians should be aware of this atypical presentation and consider anti-LGI1 encephalitis as a possible diagnosis when presented with such a neuroradiological feature.

中文翻译:

自身免疫性脑炎多发性神经根炎1例报告与综述

背景边缘脑炎是一种亚急性进行性疾病,其特征是记忆和行为障碍以及癫痫发作。针对富含亮氨酸的胶质瘤灭活 1 (LGI1) 的抗体与脑炎的一种亚型有关,该亚型与上述症状一起还以严重的疼痛和自主神经功能障碍为特征。LGI1 脑炎的典型放射学表现是单侧或双侧杏仁核和海马肿大,T2 高信号。时间外受累被认为是一种罕见的特征。病例描述 我们介绍了我们所知的唯一一例 47 岁男性抗 LGI1 脑炎的已知病例,影像学显示为背根神经节和脊神经增强。
更新日期:2020-07-02
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