Background and Aims. There seems to be a higher risk of ischemic stroke and portal vein thrombosis in liver cirrhosis. Both of them may be associated with hypercoagulability. We aim to explore the association between ischemic stroke and portal vein thrombosis in liver cirrhosis. Study Design and Methods. We selected patients from our prospectively established database of liver cirrhosis from December 2014 to July 2019. The difference between patients with and without stroke was compared. A 1 : 1 propensity score matching (PSM) analysis was performed to adjust the effect of age, sex, Child-Pugh score, and MELD score on our statistical results. Results. There were 349 cirrhotic patients in the cross-sectional study. The prevalence of stroke, ischemic stroke, hemorrhagic stroke, and portal vein thrombosis was 8.88% (31/349), 8.31% (29/349), 1.15% (4/349), and 28.65% (100/349) in liver cirrhosis, respectively. Patients with ischemic stroke were significantly older and had significantly higher proportions of alcohol abuse, smoking, and arterial hypertension and higher levels of white blood cell and low-density lipoprotein. However, statistical analyses with and without PSM did not find any significant association between ischemic stroke and portal vein thrombosis in patients with liver cirrhosis. Conclusion. Ischemic stroke might not be associated with portal vein thrombosis in liver cirrhosis.

中文翻译：

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缺血性卒中与肝硬化门静脉血栓形成之间没有关联。

背景和目标。肝硬化患者发生缺血性中风和门静脉血栓形成的风险似乎更高。它们都可能与高凝状态有关。我们旨在探讨缺血性卒中与肝硬化门静脉血栓形成之间的关系。研究设计和方法。我们从 2014 年 12 月至 2019 年 7 月前瞻性建立的肝硬化数据库中选择了患者。比较了有和没有中风的患者之间的差异。进行了 1:1 的倾向评分匹配 (PSM) 分析，以调整年龄、性别、Child-Pugh 评分和 MELD 评分对我们的统计结果的影响。结果. 在横断面研究中有 349 名肝硬化患者。中风、缺血性中风、出血性中风和门静脉血栓形成的患病率分别为8.88%（31/349）、8.31%（29/349）、1.15%（4/349）和28.65%（100/349）。肝硬化，分别。缺血性卒中患者年龄显着增加，酗酒、吸烟和动脉高血压的比例显着升高，白细胞和低密度脂蛋白水平也更高。然而，在有和没有 PSM 的情况下，统计分析并未发现肝硬化患者缺血性卒中与门静脉血栓形成之间存在任何显着关联。结论。缺血性卒中可能与肝硬化门静脉血栓形成无关。