Short bioactive peptides encoded by small open reading frames (sORFs) play important roles in eukaryotes. Bioinformatics prediction of ORFs is an early step in a genome sequence analysis, but sORFs encoding short peptides, often using non-AUG initiation codons, are not easily discriminated from false ORFs occurring by chance.

中文翻译：

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使用AnABlast在秀丽隐杆线虫基因组中进行基因间sORF预测。

由小的开放阅读框（sORF）编码的短生物活性肽在真核生物中起重要作用。ORF的生物信息学预测是基因组序列分析的第一步，但是经常使用非AUG起始密码子的编码短肽的sORF很难与偶然发生的错误ORF区分开。