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Systematic review and meta-analysis of diet quality and colorectal cancer risk: is the evidence of sufficient quality to develop recommendations?
Critical Reviews in Food Science and Nutrition ( IF 10.2 ) Pub Date : 2020-07-02 , DOI: 10.1080/10408398.2020.1786353
Sara Moazzen 1 , Kimberley W J van der Sloot 1 , Geertruida H de Bock 1 , Behrooz Z Alizadeh 1
Affiliation  

Abstract

The quality of existing evidence about the impact of diet quality on colorectal cancer (CRC) risk has only rarely been assessed. In the current review, we searched PubMed, EMBASE, Web of Science, Cochrane, and the resulting references (up to January 2020) for studies that evaluated the role of high diet quality by extreme dietary index categorization and the risk of CRC. Two researchers independently performed the study selection, data extraction, and quality assessment. We then applied a random-effects meta-analysis to estimate the pooled odds ratios (ORs) and 95% confidence intervals (CIs) for CRC at the extremes of each dietary index, and we assessed the quality of the pooled results using the Grading of Recommendations Assessment, Development and Evaluation approach. A high diet quality was significantly associated with reduced CRC risk when patients had a low Diet Inflammatory Index score (OR, 0.66; 95%CI, 0.56–0.78), a high Mediterranean Diet Score (OR, 0.84; 95%CI, 0.78–0.90), high Dietary Approaches to Stop Hypertension adherence (OR, 0.83; 95%CI, 0.78–0.89), and a high Healthy Eating Index score (OR, 0.72; 95%CI, 0.64–0.80). The pooled results for all dietary indices were rated as being of low quality due to concerns over inconsistency or imprecision. We conclude that, despite a high diet quality appearing to have a preventive role in CRC, the evidence is currently of insufficient quality to develop dietary recommendations.



中文翻译:

饮食质量和结直肠癌风险的系统评价和荟萃分析:证据质量是否足以制定建议?

摘要

关于饮食质量对结直肠癌 (CRC) 风险影响的现有证据的质量很少被评估。在当前的综述中,我们搜索了 PubMed、EMBASE、Web of Science、Cochrane 以及由此产生的参考文献(截至 2020 年 1 月),以寻找通过极端饮食指数分类和 CRC 风险评估高饮食质量的作用的研究。两名研究人员独立进行研究选择、数据提取和质量评估。然后,我们应用随机效应荟萃分析来估计每个饮食指数极端情况下 CRC 的汇总优势比 (OR) 和 95% 置信区间 (CI),并使用以下分级评估汇总结果的质量建议评估、制定和评估方法。当患者的饮食炎症指数评分较低(OR,0.66;95%CI,0.56–0.78),地中海饮食评分较高(OR,0.84;95%CI,0.78– 0.90)、停止高血压依从性的高饮食方法 (OR, 0.83; 95%CI, 0.78–0.89) 和高健康饮食指数评分 (OR, 0.72; 95%CI, 0.64–0.80)。由于担心不一致或不精确,所有饮食指数的汇总结果被评为低质量。我们得出的结论是,尽管高饮食质量似乎对 CRC 有预防作用,但目前证据质量不足以制定饮食建议。停止高血压依从性的高饮食方法 (OR, 0.83; 95%CI, 0.78–0.89) 和高健康饮食指数评分 (OR, 0.72; 95%CI, 0.64–0.80)。由于担心不一致或不精确,所有饮食指数的汇总结果被评为低质量。我们得出的结论是,尽管高饮食质量似乎对 CRC 有预防作用,但目前证据质量不足以制定饮食建议。停止高血压依从性的高饮食方法 (OR, 0.83; 95%CI, 0.78–0.89) 和高健康饮食指数评分 (OR, 0.72; 95%CI, 0.64–0.80)。由于担心不一致或不精确,所有饮食指数的汇总结果被评为低质量。我们得出的结论是,尽管高饮食质量似乎对 CRC 有预防作用,但目前证据质量不足以制定饮食建议。

更新日期:2020-07-02
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