The free radical triggered convenient synthesis of bis(indolyl)methane using various indole and aldehyde derivatives with potassium peroxodisulfate as catalyst under the ambient conditions is developed. This protocol exhibits a wide range of sterically and electronically diverse substrate scope with good to excellent yield (up to 94 %) of the desired product without affecting the bromo, chloro, iodo, nitro, methoxy, and hydroxyl groups. The experimental observation indicates that the reaction follow a radical pathway.

中文翻译：

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过二硫酸钾催化自由基引发的双（吲哚基）甲烷的便捷合成

开发了自由基引发的在环境条件下使用各种吲哚和醛衍生物，过二硫酸钾作为催化剂方便地合成双（吲哚基）甲烷的催化剂。该方案显示了范围广泛的空间和电子多样性的底物范围，具有所需产品的良好或优异的收率（高达94％），而不会影响溴，氯，碘，硝基，甲氧基和羟基。实验观察表明该反应遵循自由基途径。