Abstract In this paper, an oxygen plasma-treated ZnO nanoflower-based screen-printed electrode (SPE) is proposed as an electrochemical sensor for the simultaneous detection of dopamine (DA), and diclofenac sodium (DS). Scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy were applied to characterize the morphology and structure of the nanomaterials. The ZnO nanoflowers with a large specific surface area exhibited good electrochemical performance, and they were conducive to ion exchange. The electrochemical behaviors of DA, and DS were evaluated by cyclic voltammetry in the potential range of 0.3–1 V; the linear response ranges were 0.1–300, and 0.01–40 μM, and the sensitivities were 0.26, and 0.37 μA·μM−1 cm−2, respectively, with detection limits of 0.28, and 0.11 μM. The selective detection of DA, and DS was evaluated in the presence of other compounds. The results revealed that the oxygen plasma-treated ZnO/SPE, as an electrochemical sensor, could simultaneously detect these substances with good stability and low detection limit. The proposed method was successfully applied using urine samples, and has a good recovery rate. In the future, it may serve as a new detection technology for drug detection and health monitoring.

中文翻译：

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基于等离子体处理的氧化锌纳米花的电化学传感器同时检测多巴胺和双氯芬酸钠

摘要 在本文中，提出了一种氧等离子体处理的基于氧化锌纳米花的丝网印刷电极 (SPE) 作为同时检测多巴胺 (DA) 和双氯芬酸钠 (DS) 的电化学传感器。应用扫描电子显微镜、透射电子显微镜、能量色散 X 射线光谱、傅里叶变换红外光谱、X 射线衍射和 X 射线光电子能谱对纳米材料的形貌和结构进行表征。具有大比表面积的ZnO纳米花表现出良好的电化学性能，有利于离子交换。通过循环伏安法在 0.3-1 V 的电位范围内评估 DA 和 DS 的电化学行为；线性响应范围为 0.1-300 和 0.01-40 μM，灵敏度为 0.26 和 0. 分别为 37 μA·μM-1 cm-2，检测限分别为 0.28 和 0.11 μM。DA 和 DS 的选择性检测是在其他化合物存在的情况下进行评估的。结果表明，氧等离子体处理的 ZnO/SPE 作为电化学传感器，可以同时检测这些物质，稳定性好，检测限低。该方法已成功应用于尿液样本，并具有良好的回收率。未来可作为药物检测和健康监测的新检测技术。可以同时检测这些物质，稳定性好，检出限低。该方法已成功应用于尿液样本，并具有良好的回收率。未来可作为药物检测和健康监测的新检测技术。可以同时检测这些物质，稳定性好，检出限低。该方法已成功应用于尿液样本，并具有良好的回收率。未来可作为药物检测和健康监测的新检测技术。