Abstract Virus infections can threaten human life and health and often cause considerable losses to society. There are multiple ways for viruses to invade host cells. Therefore, it is immensely important to inhibit the contact between virus and host cell receptors. Human milk oligosaccharides (HMOs) can not only benefit the infant brain development and the immune system enhancement, but also prevent cells from virus infections due to their similar structures with viral receptors, such as histo-blood group antigens, dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin, and sialic acid receptors. In this review, we outline the current knowledge on the complex structures of HMOs and the characteristics of infection by viruses, as well as discuss the mechanisms by which HMOs protect cells against various virus invasions.

中文翻译：

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人乳寡糖的抗病毒作用：综述

摘要 病毒感染会威胁人类的生命和健康，往往会给社会造成相当大的损失。病毒入侵宿主细胞的方式有多种。因此，抑制病毒与宿主细胞受体之间的接触非常重要。人乳寡糖（HMOs）不仅有利于婴儿大脑发育和免疫系统增强，而且由于其与病毒受体的结构相似，如组织血型抗原、树突状细胞特异性细胞间粘附，可以防止细胞受到病毒感染。分子 3 抓取非整联蛋白和唾液酸受体。在这篇综述中，我们概述了目前关于 HMO 复杂结构和病毒感染特征的知识，并讨论了 HMO 保护细胞免受各种病毒入侵的机制。