We report the case of a patient with hypothalamic hamartoma (HH) who was successfully treated with magnetic resonance–guided focused ultrasound (MRgFUS) for ablation as a disconnection surgery. A 26-year-old man with gelastic epilepsy had been diagnosed with HH at 3 years of age, and antiepileptic drugs were administered due to worsening episodes. Magnetic resonance imaging showed a sessile parahypothalamic hamartoma and MRgFUS ablation was performed, creating an oval-shaped lesion at the boundary area of the HH. Dramatic improvements in seizure symptoms were noted, and he was seizure-free on decreased antiepileptic drugs without any adverse events over the 1-year follow-up period.

我们报道了下丘脑错构瘤（HH）患者的病例，该患者已成功通过磁共振引导聚焦超声（MRgFUS）作为断层手术消融。一名26岁的全弹性癫痫患者在3岁时被诊断出患有HH，并且由于发作恶化而服用了抗癫痫药。磁共振成像显示无柄下丘脑错构瘤，并进行了MRgFUS消融，在HH的边界区域形成了椭圆形的病变。注意到癫痫发作症状有显着改善，并且在1年的随访期内，他因抗癫痫药减少而无癫痫发作，无任何不良事件。