Ternary extractive distillation (TED) is an effective and sustainable separation process for treating pharmaceutical wastewater containing ethyl acetate/isopropanol/water, corresponding to three binary azeotropes, to realize the recovery of ethyl acetate and isopropanol. Visual Basic software was used to optimize the extractive distillation process using a single solvent and mixed solvent in different proportions based on a sequential iterative optimization method, and the optimal mixture proportion (30% DMSO+70% EG) of the mixed solvent was determined. The economic and environmental performance of the extractive distillation process with a mixed solvent combined with partial thermal coupling technology was studied. The heat recovery within the separation process was further improved by the energy-efficient heat exchanger network synthesis (HENs) option. The economic and environmental performance of the mixed solvent extractive distillation process combined with heat pump technology was also explored. The results show that for the ternary extractive distillation process, the use of mixed solvent can significantly reduce energy consumption, which can lead to lower total annual cost (TAC) and CO₂ emission. Compared with a conventional separation process with mixed solvent, the extractive distillation process combined with partial thermal coupling and heat pump technology further improves the economic and environmental performance. The TAC and CO₂ emission of the mixed solvent separation process combined with partial thermal coupling technology were reduced by 12.183% and 19.869%, respectively. The TAC and CO₂ emission of the mixed solvent separation process combined with heat pump distillation technology were reduced by 34.782% and 37.156%, respectively, which indicates the feasibility of using these two energy-saving processes for continuously updated cleaner production.

中文翻译：

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混合溶剂萃取蒸馏与热耦合或热泵技术相结合用于分离低碳酒精共沸物的节能研究

三元萃取蒸馏（TED）是一种有效且可持续的分离工艺，用于处理含乙酸乙酯/异丙醇/水（对应于三种二元共沸物）的制药废水，以实现乙酸乙酯和异丙醇的回收。使用Visual Basic软件基于顺序迭代优化方法，使用单一溶剂和混合溶剂以不同比例优化萃取蒸馏过程，并确定混合溶剂的最佳混合比例（30％DMSO + 70％EG）。研究了混合溶剂萃取与部分热耦合技术相结合的萃取蒸馏工艺的经济和环境性能。高效的热交换器网络综合（HENs）选项进一步提高了分离过程中的热回收率。还探讨了混合溶剂萃取蒸馏工艺与热泵技术相结合的经济和环境性能。结果表明，对于三元萃取蒸馏过程，使用混合溶剂可以显着降低能耗，从而可以降低年度总成本（TAC）和一氧化碳₂发射。与传统的混合溶剂分离工艺相比，萃取蒸馏工艺与部分热耦合技术和热泵技术相结合，进一步提高了经济和环境性能。结合部分热偶合技术的混合溶剂分离工艺的TAC和CO ₂排放分别降低了12.183％和19.869％。混合溶剂分离工艺与热泵蒸馏技术相结合的TAC和CO ₂排放量分别减少了34.782％和37.156％，这表明使用这两种节能工艺连续更新清洁生产的可行性。