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Linezolid-resistant (Tn6246::fexB-poxtA) Enterococcus faecium strains colonizing humans and bovines on different continents: similarity without epidemiological link.
Journal of Antimicrobial Chemotherapy ( IF 5.2 ) Pub Date : 2020-07-01 , DOI: 10.1093/jac/dkaa227
Ana R Freitas 1 , Ana P Tedim 1, 2 , Bárbara Duarte 1, 3 , Houyem Elghaieb 4 , Mohamed S Abbassi 4 , Abdennaceur Hassen 5 , Antónia Read 6 , Valquíria Alves 6 , Carla Novais 1 , Luísa Peixe 1
Affiliation  

poxtA is the most recently described gene conferring acquired resistance to linezolid, a relevant antibiotic for treating enterococcal infections. We retrospectively screened for poxtA in diverse enterococci and aimed to characterize its genetic/genomic contexts.

中文翻译:

耐利奈唑酮(Tn6246 :: fexB-poxtA)粪肠球菌菌株在不同大陆上的人和牛定居:相似性没有流行病学联系。

poxtA是最近描述的赋予对利奈唑胺的获得性耐药的基因,利奈唑胺是一种治疗肠球菌感染的相关抗生素。我们回顾性筛选了多种肠球菌中的poxtA,旨在表征其遗传/基因组背景。
更新日期:2020-08-24
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