MicroRNAs (miRNAs) are small non-coding RNAs that have been successfully identified to be differentially expressed in various cancers. However, some miRNAs were reported to be up-regulated in one subtype of a cancer but down-regulated in another, making overall associations between these miRNAs and the heterogeneous cancer non-linear. These non-linearly associated miRNAs, if identified, are thus informative for cancer subtyping.

中文翻译：

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mirPLS：使用MicroRNA进行癌症亚型化的部分线性结构识别方法。

微小RNA（miRNA）是小的非编码RNA，已被成功鉴定为在各种癌症中差异表达。但是，据报道，某些miRNA在一种癌症亚型中被上调，而在另一种癌症中被下调，这使得这些miRNA与异种癌症之间的整体关联呈非线性。如果识别出这些非线性相关的miRNA，则有助于癌症分型。