Many individuals perform cell viability assays as a measure of biocompatibility whether the focus of their research is on novel drug discovery, development of novel biomedical devices, or the study of biointerfacial phenomena. In this tutorial paper, the most commonly used methods available to users to perform biocompatibility testing are discussed. This includes a brief introduction into the benefits and drawbacks of the techniques, including which are best used as screening assays, which are better suited to experienced users, the relative cost of the assays per unit, and what detection techniques are most appropriate for use in conjunction with the assays. In addition to helping users ensure the rigor and reproducibility of their research design, this tutorial is meant to assist reviewers of interdisciplinary journals (such as Biointerphases itself), whose expertise is in other areas of this research but do not have the experience with cell-based assays themselves.

中文翻译：

---

如何选择在生物界面上对哺乳动物细胞进行细胞毒性分析的适当方法：教程。

无论他们研究的重点是新型药物的发现，新型生物医学设备的开发，还是生物界面现象的研究，许多人都进行细胞生存力测定来衡量生物相容性。在本教程文件中，讨论了用户可用来执行生物相容性测试的最常用方法。其中包括对技术优势和劣势的简要介绍，其中包括最适合用作筛选分析的方法，更适合经验丰富的用户，每单位分析的相对成本以及最适合用于哪种检测技术的方法。结合测定。除了帮助用户确保研究设计的严谨性和可重复性之外，本教程还旨在帮助跨学科期刊（例如Biointerphases本身），其专业知识是本研究的其他领域，但本身没有基于细胞的测定的经验。