The preparation of pyrazolo pyrimidinone derivatives was performed by using five component reactions of phthalaldehyde, cyanomethylamine, electron deficient acetylenic compounds, isocyanate, hydrazine, and catalytic amounts of ZnO/Fe₃O₄‐magnetic nanoparticles as a high performance catalyst under ultrasonic conditions at ambient temperature in aquause media at room temperature. It should be mentioned that this catalyst was prepared using Spinacia oleracea water extract. In addition, for investigation of antioxidant ability, radical trapping by DPPH and reducing power of ferric ion experiments was performed. As a result, synthesized compounds show excellent radical trapping by DPPH and good reducing ability of ferric ion. The current procedure has the benefits for instance excellent yield of reaction, green media, and easy separation of product and catalyst.

中文翻译：

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ZnO / Fe3O4纳米颗粒促进吡唑并嘧啶酮的绿色合成：抗氧化活性的研究

吡唑并嘧啶酮衍生物的制备是在环境条件下，在超声条件下，利用苯甲醛，氰基甲胺，电子缺陷型炔属化合物，异氰酸酯，肼和催化量的ZnO / Fe ₃ O ₄磁性纳米颗粒的五种组分反应进行的。室温下在水族介质中的温度。应该提到的是，该催化剂是用菠菜制备的。水提取物。另外，为了研究抗氧化能力，进行了通过DPPH的自由基俘获和铁离子还原能力的实验。结果，合成的化合物显示出优异的被DPPH捕获的自由基和良好的铁离子还原能力。当前的方法具有例如优异的反应产率，绿色介质以及产物和催化剂易于分离的优点。