Obesity has become a very large concern worldwide, reaching pandemic proportions over the past several decades. Lifestyle factors, such as excess caloric intake and decreased physical activity, together with genetic predispositions, are well-known factors related to obesity. There is accumulating evidence suggesting that exposure to some environmental chemicals during critical windows of development may contribute to the rapid increase in the incidence of obesity. Agrochemicals are a class of chemicals extensively used in agriculture, which have been widely detected in human. There is now considerable evidence linking human exposure to agrochemicals with obesity. This review summarizes human epidemiological evidence and experimental animal studies supporting the association between agrochemical exposure and obesity and outlines possible mechanistic underpinnings for this link.

肥胖已成为世界范围内的一个非常大的问题，在过去几十年中达到了大流行的程度。生活方式因素，例如热量摄入过多和体力活动减少，以及遗传倾向，都是众所周知的与肥胖相关的因素。越来越多的证据表明，在发育的关键窗口期间接触某些环境化学物质可能会导致肥胖发生率迅速增加。农用化学品是一类广泛用于农业的化学品，已在人体中广泛检测到。现在有大量证据表明人类接触农用化学品与肥胖有关。