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Effects of agricultural pesticides on the reproductive system of aquatic wildlife species, with crocodilians as sentinel species.
Molecular and Cellular Endocrinology ( IF 4.1 ) Pub Date : 2020-06-30 , DOI: 10.1016/j.mce.2020.110918
Y E Tavalieri 1 , G H Galoppo 1 , G Canesini 1 , E H Luque 1 , M M Muñoz-de-Toro 1
Affiliation  

Agricultural pesticides represent a significant class of endocrine-disrupting chemicals (EDCs) to which non-target organisms around the world are constantly exposed. Laboratory studies have found strong evidence showing the endocrine-disruptive potential of these pesticides at environmentally relevant exposure levels. Since the field of endocrine disruption continues to grow in richness and complexity, this review aims to provide an update on the effects of two agricultural pesticides that act as EDCs: atrazine and endosulfan. We will focus mainly on the effects on crocodilians due to their worldwide occurrence in tropical and sub-tropical wetland ecosystems and their ecological and physiological features, which render them vulnerable to exposure to pesticides with endocrine-disrupting action at all life stages. The results here reviewed provide important insights into the effects of hormonally active agricultural pesticides at cellular, tissue, and organ levels in the reproductive system of crocodiles. A better understanding of the effects of exposure to environmentally relevant doses of EDCs on the reproductive system of crocodilians will contribute to protect and improve the health of both wildlife species and humans.



中文翻译:

农业农药对以鳄鱼为前哨物种的水生野生生物生殖系统的影响。

农业杀虫剂是一类重要的破坏内分泌的化学物质(EDC),世界各地的非目标生物一直在接触这些化学物质。实验室研究发现有力的证据表明,在与环境有关的接触水平下,这些农药具有破坏内分泌的潜能。由于内分泌干扰领域的丰富性和复杂性不断增长,因此本综述旨在提供两种充当EDC的农业农药的作用的最新信息:阿特拉津和硫丹。我们将主要关注对鳄鱼的影响,因为它们在全世界的热带和亚热带湿地生态系统中广泛存在,并具有生态和生理特征,使它们在生命的各个阶段都容易受到具有内分泌干扰作用的农药的影响。本文审查的结果为鳄鱼活性生殖农药在细胞,组织和器官水平上对激素活性农业农药的作用提供了重要的见解。更好地了解环境相关剂量的EDC对鳄鱼的生殖系统的影响,将有助于保护和改善野生动植物物种和人类的健康。

更新日期:2020-07-01
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