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Bilirubin in metabolic syndrome and associated inflammatory diseases: New perspectives
Life Sciences ( IF 6.1 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.lfs.2020.118032
Petr Novák 1 , Ampadu O Jackson 2 , Guo-Jun Zhao 3 , Kai Yin 4
Affiliation  

Diabetes mellitus is one of the major global health issues, which is closely related to metabolic dysfunction and the chronic inflammatory diseases. Multiple studies have demonstrated that serum bilirubin is negatively correlated with metabolic syndrome and associated inflammatory diseases, including atherosclerosis, hypertension, etc. However, the roles of bilirubin in metabolic syndrome and associated inflammatory diseases still remain unclear. Here, we explain the role of bilirubin in metabolic syndrome and chronic inflammatory diseases and its therapeutic potential. Understanding the role of bilirubin activities in diabetes may serve as a therapeutic target for the treatment of chronic inflammatory diseases in diabetic patients.

中文翻译:

胆红素在代谢综合征和相关炎症性疾病中的作用:新观点

糖尿病是全球主要健康问题之一,与代谢功能障碍和慢性炎症性疾病密切相关。多项研究表明,血清胆红素与代谢综合征及相关炎症性疾病,包括动脉粥样硬化、高血压等呈负相关。然而,胆红素在代谢综合征及相关炎症性疾病中的作用仍不清楚。在这里,我们解释胆红素在代谢综合征和慢性炎症性疾病中的作用及其治疗潜力。了解胆红素活性在糖尿病中的作用可以作为治疗糖尿病患者慢性炎症性疾病的治疗靶点。
更新日期:2020-07-01
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