More and more various chemical media are being applied in enantioseparation; among them, ionic liquids (ILs) have attracted the long-term attention in this decade as green designable solvents. This paper provides comprehensive overview for the applications of ILs in chiral extraction, gas chromatography, liquid chromatography, capillary electrophoresis and other techniques for enantioseparation. Additionally, the important resolution mechanisms based on ILs have also been summarized and discussed. This review focuses on the latest development of enantioseparation methods by using ILs in various modes, leading to meaningful and valuable information to related fields and thus promotes further research and application of reported methods.

对映体分离中使用了越来越多的各种化学介质。其中，离子液体（ILs）作为绿色可设计溶剂已在本十年中引起了长期关注。本文概述了IL在手性萃取，气相色谱，液相色谱，毛细管电泳和其他对映体分离技术中的应用。另外，还总结和讨论了基于IL的重要解析机制。这篇综述着重于通过以各种模式使用IL来对映体分离方法的最新发展，从而为相关领域带来有意义和有价值的信息，从而促进了报道方法的进一步研究和应用。