当前位置: X-MOL 学术J. Biomech. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Mechanobiological based long bone growth model for the design of limb deformities correction devices.
Journal of Biomechanics ( IF 2.4 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.jbiomech.2020.109905
M G Alonso 1 , G Bertolino 1 , A Yawny 1
Affiliation  

A mechanobiological model of bone growth aimed for the design of medical devices for the treatment of limb deformities during childhood and adolescence was developed. Dimensional analysis was introduced as a tool for the systematic evaluation of the influence attributed to different factors that might modify the bone growth process. Simplifications were proposed, allowing the reduction of bone growth relevant parameters to four non-dimensional numbers, representing the chondrocyte sensitivity to stress, the epiphyseal plate geometry, the bone rigidity and the time. Benchmark situations considered for model validation were bone growth under normal conditions and an epiphyseal stapling treatment. A finite elements approach was used to analyze bone growth in the distal portion of the femur. Results are shown to be consistent with corresponding clinical data published in the literature, which indicates the potential of the here proposed method for the design of specific devices and treatments.



中文翻译:

基于力学生物学的长骨生长模型,用于肢体畸形矫正设备的设计。

建立了旨在设计用于治疗儿童和青少年肢体畸形的医疗设备的骨骼生长的力学生物学模型。引入了尺寸分析作为系统评估归因于可能会影响骨骼生长过程的不同因素的影响的工具。提出了简化方法,可以将与骨生长相关的参数减少到四个无量纲的数字,分别代表软骨细胞对压力的敏感性,骨s板的几何形状,骨的刚度和时间。考虑用于模型验证的基准情况是正常条件下的骨生长和骨phy吻合治疗。使用有限元方法分析股骨远端的骨生长。

更新日期:2020-07-13
down
wechat
bug