Optical coherence tomography angiography (OCTA) is a rapidly developing technique which generates angiographic images non-invasively. This study proposes a method to determine the vessel density in OCTA scans in general and especially the local peripapillary vessel density. The method produces vessel density heatmaps that contain information about the local vessel density. We apply the method in a small study to demonstrate its applicability and its potential to investigate the influence of local conditions on the vessel density. In the study, we combine information from enhanced depth imaging optical coherence tomography (EDI-OCT) about the location of optic disc drusen (ODD) with information from OCTA about the vessel density. We see a reduction in local peripapillary vessel density in peripapillary sections with a large volume of ODD.

光学相干断层扫描血管造影（OCTA）是一项快速发展的技术，可无创地生成血管造影图像。这项研究提出了一种确定OCTA扫描中血管密度的方法，特别是局部乳头周围血管密度。该方法产生包含关于局部血管密度的信息的血管密度热图。我们在一项小型研究中应用了该方法，以证明其适用性和研究局部条件对血管密度的影响的潜力。在这项研究中，我们将增强深度成像光学相干断层扫描（EDI-OCT）中有关视盘玻璃膜疣（ODD）位置的信息与OCTA中有关血管密度的信息相结合。我们发现，ODD量较大时，乳头周围部分的局部乳头周围血管密度会降低。