Contact Lens & Anterior Eye ( IF 3.2 ) Pub Date : 2020-06-30 , DOI: 10.1016/j.clae.2020.06.002 Sònia Travé-Huarte 1 , James S Wolffsohn 1
Purpose
To determine the effectiveness of the Aurai water propelled, heating Eye Massager (AEM) in managing dry eye disease and its effects on the ocular adnexa.
Methods
This prospective, randomised cross-over study enrolled 15 participants (aged 25.8 ± 5.45 years, 5 male). Participants wore a smart watch 24 h a day to track their sleeping cycle and heart rate for 4 weeks, using the AEM twice a day for 2 of those weeks. A cycle of 6 min of a controlled heat and vibration pattern in the morning and another cycle in the evening were applied with the AEM. Primary outcomes of symptomatology (Ocular Surface Disease Index (OSDI) and Symptom Assessment iN Dry Eye (SANDE)), tear film and ocular surface homeostasis markers (osmolarity, non-invasive breakup time (NIKBUT), tear meniscus height (TMH), lipid layer thickness and ocular staining) and safety measures (ocular redness and intraocular pressure), were assessed at baseline, after 2 weeks of AEM use and after 2 weeks of no treatment (in random-sequence). Sleeping tracking (ST) and heart rate/blood oxygen detection over these periods was also assessed.
Results
There was a significant change in OSDI score from 34.3 ± 19.5 at baseline to 18.8 ± 17.5 after treatment (p = 0.001) and also for the SANDE (5.7 ± 2.4 vs 3.7 ± 2.1; p = 0.001). Heart rate was not affected by treatment (p = 0.956), nor sleep pattern (p = 0.529), but this varied by day (p = 0.001). Tear film and ocular surface homeostasis, the ocular adnexia and safety measures were not affected by treatment (p > 0.05).
Conclusion
The Aurai water propelled Eye Massager may reduce the severity of symptoms of dry eye, but there were no detectable effects on tear stability and ocular surface disease from two weeks use.
中文翻译:
新型水推进加热眼罩按摩器对泪膜和眼附件的疗效
目的
确定 Aurai 水推进式加热眼部按摩器 (AEM) 在治疗干眼症方面的有效性及其对眼附件的影响。
方法
这项前瞻性随机交叉研究招募了 15 名参与者(年龄 25.8 ± 5.45 岁,5 名男性)。参与者每天佩戴智能手表 24 小时以跟踪他们的睡眠周期和心率 4 周,其中 2 周每天使用 AEM 两次。使用 AEM 应用早上 6 分钟的受控加热和振动模式循环和晚上的另一个循环。症状学的主要结果(眼表疾病指数 (OSDI) 和干眼症状评估 (SANDE))、泪膜和眼表稳态标志物(渗透压、非侵入性破裂时间 (NIKBUT)、泪液半月板高度 (TMH)、脂质层厚度和眼部染色)和安全措施(眼部发红和眼内压)在基线、使用 AEM 2 周后和未治疗 2 周后(随机顺序)进行评估。
结果
OSDI 评分从基线时的 34.3 ± 19.5 到治疗后的 18.8 ± 17.5 (p = 0.001) 以及 SANDE 的显着变化(5.7 ± 2.4 vs 3.7 ± 2.1;p = 0.001)。心率不受治疗 (p = 0.956) 和睡眠模式 (p = 0.529) 的影响,但每天都会有所不同 (p = 0.001)。泪膜和眼表稳态、眼附件和安全措施不受治疗影响(p > 0.05)。
结论
Aurai 水推进眼部按摩器可能会减轻干眼症症状的严重程度,但使用两周后对泪液稳定性和眼表疾病没有明显影响。