Sub-lethal toxic impacts of chromium on hematological, biochemical and histological parameters were analyzed in the female small Indian mongoose (Urva auropuctatus) residing contaminated environment of tannery industry. Chromium bioaccumulation in the blood, liver and kidney tissue of the exposed mongooses was found elevated compared to the control mongooses’ tissues. Total body weight (75.7%), liver weight (83.6%) as well as HSI (68.1%), RSI (86.2%) and the platelets counts (59.7%) were found significantly elevated, with significantly reduced RBCs (59.6%), and WBCs (64%). LFT and RFT were also found abnormal, moreover, the histopathological injuries had been distinct inside the kidney (>75%) and hepatic (>75%) tissues of exposed animals. Shrinkage and vacuolization (>75%) inside the hepatocyte expanded sinusoidal spaces and nuclear pyknosis (>75%) was evident within the hepatic tissue. Hypertrophy of epithelial cells of renal tubules and inter-renal cells of the head kidney with a reduction in tubular lumens (>75%) and vacuolization of tubules were witnessed within the kidney section. Atrophy inside the kidney inter-renal cells, glomeruli compression within the Bowman’s capsules (>75%) following the necrosis in hematopoietic tissues were found in exposed animals. The present findings indicate that chronic exposure to chromium induces severe anemia, decreased serum protein concentration, hepatic and renal tissue histopathology, impairing the vital capabilities of liver, metabolic regulation, excretion, and stress homeostasis maintenance of which within the long-run may posture a severe risk to animal well-being then distress their inhabitants.

在雌性印度小猫鼬（Urva auropuctatus）中分析了铬对血液，生物化学和组织学参数的亚致命毒性影响处于制革业受污染的环境中。发现暴露的猫鼬的血液，肝脏和肾脏组织中的铬生物富集度高于对照猫鼬的组织。发现总体重（75.7％），肝脏重量（83.6％）以及HSI（68.1％），RSI（86.2％）和血小板计数（59.7％）显着升高，而RBC显着减少（59.6％），和白细胞（64％）。还发现LFT和RFT异常，此外，暴露动物的肾脏组织（> 75％）和肝组织（> 75％）的组织病理学损伤明显。肝细胞内的收缩和空泡（> 75％）扩大了正弦波空间，并且在肝组织内明显出现核固缩（> 75％）。肾部分可见肾小管上皮细胞肥大和头部肾脏的肾间细胞肥大，肾小管腔减少（> 75％）和肾小管空泡。在裸露的动物中，发现造血组织坏死后，肾脏肾间质细胞内萎缩，鲍曼氏囊内的肾小球受压（> 75％）。目前的发现表明，长期暴露于铬会引起严重的贫血，血清蛋白浓度降低，肝和肾组织的组织病理学，损害肝脏的生命力，代谢调节，排泄和应激稳态的维持，从长远来看，这可能会导致肝硬化。严重危害动物福祉的人随后使他们的居民受苦。75％）和肾小管的小管空泡。在裸露的动物中，发现造血组织坏死后，肾脏肾间质细胞内萎缩，鲍曼氏囊内的肾小球受压（> 75％）。目前的发现表明，长期暴露于铬会引起严重的贫血，血清蛋白浓度降低，肝和肾组织的组织病理学，损害肝脏的生命力，代谢调节，排泄和应激稳态的维持，从长远来看，这可能会导致肝硬化。严重危害动物福祉的人随后使他们的居民受苦。75％）和肾小管的小管空泡。在裸露的动物中，发现造血组织坏死后，肾脏肾间质细胞内萎缩，鲍曼氏囊内的肾小球受压（> 75％）。目前的发现表明，长期暴露于铬会引起严重的贫血，血清蛋白浓度降低，肝和肾组织的组织病理学，损害肝脏的生命力，代谢调节，排泄和应激稳态的维持，从长远来看，这可能会导致肝硬化。严重危害动物福祉的人随后使他们的居民受苦。