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Bifunctional CuS composite nanofibers via in situ electrospinning for outdoor rapid hemostasis and simultaneous ablating superbug
Chemical Engineering Journal ( IF 15.1 ) Pub Date : 2020-06-30 , DOI: 10.1016/j.cej.2020.126096
Xiao-Fei Liu , Jun Zhang , Jiang-Jun Liu , Qi-Hui Zhou , Zhongqiang Liu , Peng-Yue Hu , Zhe Yuan , Seeram Ramakrishna , Da-Peng Yang , Yun-Ze Long

Outdoor sports or combat missions, such as jungle adventures or counter-piracy operations, often involve bleeding and infected wounds. Due to the poor and limited medical conditions in these outdoor situations, patients prefer an easy way to simultaneously treat blood loss and wound infection by using the same outdoor device and the same material. In this study, a portable electrospinning device (150 g in weight) for outdoor use was developed, and CuS composite nanofibers could be green-synthesized by this portable electrospinning device. These CuS composite nanofibers can be deposited in situ onto the wound to simultaneously achieve rapid hemostasis outdoors and ablate superbacteria without requiring the use of other materials or devices. These in situ electrospun nanofibers possess better compactness on the rough wound surface than conventional nanofiber mats pressed onto the wound site. Thus, the nanofiber not only accelerates the hemostasis (<6 s) but also shortens the healing time of the wound with superbacterial infection (18 days). These bifunctional nanofibers combined with a portable electrospinning device for outdoor rapid hemostasis and simultaneous superbug ablation could notably benefit the outdoor first aid.



中文翻译:

双功能CuS复合纳米纤维通过原位静电纺丝进行室外快速止血并同时消融超级细菌

户外运动或战斗任务(例如丛林探险或反海盗行动)通常涉及出血和感染伤口。由于在这些户外情况下医疗条件恶劣且有限,患者喜欢使用一种简单的方法,即使用相同的户外设备和相同的材料同时治疗失血和伤口感染。在这项研究中,开发了一种用于户外的便携式静电纺丝设备(重量为150 g),并且该便携式静电纺丝设备可以绿色合成CuS复合纳米纤维。这些CuS复合纳米纤维可原位沉积伤口上,从而在户外实现快速止血并消融超级细菌,而无需使用其他材料或装置。这些就地电纺纳米纤维在粗糙的伤口表面上具有比压在伤口部位的传统纳米纤维垫更好的致密性。因此,纳米纤维不仅加速了止血(<6 s),而且缩短了超细菌感染伤口的愈合时间(18天)。这些双功能纳米纤维与便携式静电纺丝设备相结合,可实现户外快速止血和同时进行超级除虫消融,从而显着受益于户外急救。

更新日期:2020-07-03
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