Truxinic acid sucrose diesters analogs possess interesting chemical structure by the presence of cyclobutane-ring and macrocyclic sucrose diesters moieties which are rarely found from natural sources. This paper describes the isolation and structural elucidation of four new sucrose diesters of substituted truxinic acids, trigohonbanosides A-D (1–4), from the leaves of Trigonostemon honbaensis. Their chemical structures were elucidated by HR-ESI-MS, NMR, and CD spectroscopic methods. At a concentration of 30 µM, compounds 1–4 moderately inhibited ANO-1 activity with inhibitory percentages of 27.7 ± 1.10%, 35.6 ± 0.92%, 43.7 ± 1.61%, and 40.8 ± 1.25%, respectively.

由于存在于天然来源中很少发现的环丁烷环和大环蔗糖二酯部分，因此杜鹃酸蔗糖二酯类似物具有令人感兴趣的化学结构。本文描述了分离和取代truxinic酸，trigohonbanosides AD（四个新的蔗糖二酯结构解析1 - 4）中，从叶三宝木属honbaensis。通过HR-ESI-MS，NMR和CD光谱法阐明了它们的化学结构。在30μM的浓度，化合物1 - 4 27.7±1.10％的抑制百分数分别适度抑制ANO-1活性，35.6±0.92％，43.7±1.61％，和40.8±1.25％。