Abstract

Sensors for the potentiometric determination of mefenamic and phenylanthranylic acids are prepared on the basis of single- and the double-layer plasticized polyvinylchloride membranes. Ion pairs of perchlorate and mefenamic and phenylanthranylic acid with basic fuchsin are synthesized for the fabrication of membranes. The composition of compounds is confirmed by spectrophotometry and IR spectrometry. Effects of different factors on the electrode characteristics are studied, the composition of the membranes is optimized. The proposed procedure for the fabrication of double-layer membranes ensures the improvement of the properties of sensors for mefenamic and phenylanthranylic acids. The developed procedures are applied to the analysis of pharmaceutical preparations.

中文翻译：

---

基于单层和双层增塑膜的传感器，用于电位分析法测定甲芬那酸和邻苯二甲酸

摘要

在单层和双层增塑的聚氯乙烯膜的基础上，制备了电位测定甲芬那酸和苯基蒽酸的传感器。合成了高氯酸根离子，对甲amic酸和苯基蒽酸与碱性品红的离子对，用于制造膜。化合物的组成通过分光光度法和红外光谱法确认。研究了不同因素对电极特性的影响，优化了膜的组成。所提出的用于制造双层膜的程序确保了用于芬那美和苯基蒽酸的传感器性能的改善。所开发的程序适用于药物制剂的分析。