Background:Advances in the treatment of Parkinson’s disease (PD) have allowed for improvements in mortality and quality survival, making the management of comorbid conditions of aging, such as osteoarthritis, crucial. Objective:To determine the extent to which PD impacts hospitalization outcomes after an elective orthopedic procedure. Methods:This retrospective cohort study used data from the National Readmissions Database and included adults ages 40 and above with and without PD. Primary outcomes included length of stay of the index admission, discharge disposition and 30-day readmission. Logistic regression was used to compare the odds of readmission for PD patients compared to non-PD. Clinical conditions associated with readmission were compared between the two groups. Results:A total of 4,781 subjects with PD and 947,475 subjects without PD met inclusion criteria. Length of stay (LOS) during the index admission was longer for PD patients. PD patients were much more likely to be discharged to inpatient post-acute care (49.3% vs 26.2%) while non-PD subjects were more likely to be discharged home with (31.9% [PD] vs 44.8% [non-PD]) or without home health (18.7% [PD] vs 28.9% [non-PD]). A total of 271 PD patients (5.66%) and 28,079 non-PD patients (2.96%) were readmitted within 30 days following surgery. After adjusting for age, sex, socioeconomic status, expected payer, comorbidities, index admission LOS, year and discharge disposition, PD subjects were 31% more likely to be readmitted than non-PD subjects (AOR 1.31, 1.07–1.62). Conclusions:Parkinson’s disease patients were readmitted more often than non-PD patients, although the rate of readmission was still low.

中文翻译：

---

选择性整形外科手术结果的帕金森病相关差异：国家再入院数据库分析。

背景：帕金森病 (PD) 治疗的进步提高了死亡率和生存质量，这使得对衰老合并症（如骨关节炎）的管理变得至关重要。目的：确定选择性骨科手术后 PD 对住院结果的影响程度。方法：这项回顾性队列研究使用来自国家再入院数据库的数据，包括 40 岁及以上患有和不患有 PD 的成年人。主要结果包括指数入院的住院时间、出院处置和 30 天再入院。Logistic 回归用于比较 PD 患者与非 PD 患者再入院的几率。比较两组与再入院相关的临床状况。结果：共有 4,781 名 PD 受试者和 947 名受试者，475 名没有 PD 的受试者符合纳入标准。PD 患者在首次入院期间的住院时间 (LOS) 更长。PD 患者更有可能出院接受住院后急性护理（49.3% 对 26.2%），而非 PD 受试者更有可能出院回家（31.9% [PD] 对 44.8% [非 PD]）或没有家庭健康（18.7% [PD] vs 28.9% [非 PD]）。手术后 30 天内，共有 271 名 PD 患者（5.66%）和 28,079 名非 PD 患者（2.96%）再次入院。在调整年龄、性别、社会经济地位、预期付款人、合并症、入院指数 LOS、年份和出院处置后，PD 受试者比非 PD 受试者再次入院的可能性高 31%（AOR 1.31、1.07-1.62）。结论：帕金森病患者的再入院率高于非 PD 患者，但再入院率仍然较低。