BACKGROUND:Blackberries have a high content of bioactive compounds such as anthocyanins and ellagitannins, which are associated with health benefits against cardiovascular diseases, cancer, diabetes, and other inflammatory conditions. OBJECTIVE:This study evaluated the effect of a tropical highlandblackberry (Rubus adenotrichos Schltdl.) beverage (50% v/v) on lipids, glucose and antioxidant parameters of healthy individuals. METHODS:Thirteen healthy individuals of both sexes were assigned into two groups in a randomized crossover design. Each participant was subjected to a high fat and high carbohydrate diet challenge and drank 250 mL of either blackberry beverage or water with every meal, three times a day for 14 days. Total cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, glucose level, superoxide dismutase (SOD), and catalase (CAT) enzymatic activities were assessed from plasma. RESULTS:Plasma levels of triglycerides, total cholesterol, and glucose levels significantly decreased (p < 0.05) after consuming the blackberry beverage. Changes in LDL and HDL cholesterol levels were not statistically significant (p > 0.05).CAT and SOD enzymatic activities increased slightly, although not statistically significant (p > 0.05). CONCLUSION:Drinking a beverage from a blackberry micro-filtered juice improved plasma lipid and glucose profiles, as well as CATand SOD enzymatic activities in healthy participants.

中文翻译：

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健康个体在高脂，高碳水化合物饮食挑战下食用热带高地黑莓饮料的降脂，降血糖和抗氧化作用

背景：黑莓具有高含量的生物活性化合物，如花青素和鞣花单宁，它们具有对抗心血管疾病，癌症，糖尿病和其他炎症的健康益处。目的：本研究评估了一种热带高原黑莓（Rubus adenotrichos Schltdl。）饮料（50％v / v）对健康个体的脂质，葡萄糖和抗氧化参数的影响。方法：采用随机交叉设计，将十三名男女健康者分为两组。每位参与者都接受高脂肪和高碳水化合物饮食的挑战，每餐每餐饮用250毫升黑莓饮料或水，每天3次，共14天。总胆固醇，甘油三酸酯，低密度脂蛋白胆固醇，高密度脂蛋白胆固醇，葡萄糖水平，超氧化物歧化酶（SOD），从血浆中评估过氧化氢酶和过氧化氢酶（CAT）的酶活性。结果：饮用黑莓饮料后，血浆甘油三酸酯，总胆固醇和葡萄糖水平显着降低（p <0.05）。LDL和HDL胆固醇水平的变化无统计学意义（p> 0.05）。CAT和SOD酶活性略有增加，尽管无统计学意义（p> 0.05）。结论：从黑莓微滤汁中饮用饮料可改善健康参与者的血浆脂质和葡萄糖谱以及CAT和SOD的酶活性。LDL和HDL胆固醇水平的变化无统计学意义（p> 0.05）。CAT和SOD酶活性略有增加，尽管无统计学意义（p> 0.05）。结论：从黑莓微滤汁中饮用饮料可改善健康参与者的血浆脂质和葡萄糖谱以及CAT和SOD的酶活性。LDL和HDL胆固醇水平的变化无统计学意义（p> 0.05）。CAT和SOD酶活性略有增加，尽管无统计学意义（p> 0.05）。结论：从黑莓微滤汁中饮用饮料可改善健康参与者的血浆脂质和葡萄糖谱以及CAT和SOD的酶活性。