Abstract: Neoadjuvant chemotherapy is increasingly used in breast cancer, especially for downstaging the primary tumor in the breast and the metastatic axillary lymph node. Accurate evaluations of the response to neoadjuvant chemotherapy provide important information on the impact of systemic therapies on breast cancer biology, prognosis, and guidance for further therapy. Moreover, pathologic complete response is a validated and valuable surrogate prognostic factor of survival after therapy. Evaluations of neoadjuvant chemotherapy response are very important in clinical work and basic research. In this review, we will elaborate on evaluations of the efficacy of neoadjuvant chemotherapy in breast cancer and provide a clinical evaluation procedure for neoadjuvant chemotherapy.

Keywords: neoadjuvant chemotherapy, breast cancer, evaluations of response


中文翻译：

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新辅助化疗对乳腺癌的疗效评估。

摘要：新辅助化疗在乳腺癌中的应用越来越广泛，尤其是用于降低乳腺癌的原发性肿瘤和转移性腋窝淋巴结的转移。对新辅助化疗反应的准确评估可提供有关全身疗法对乳腺癌生物学的影响，预后以及进一步治疗指南的重要信息。此外，病理完全缓解是治疗后生存的有效且有价值的替代预后因素。新辅助化疗反应的评估在临床工作和基础研究中非常重要。在这篇综述中，我们将详细介绍新辅助化疗在乳腺癌中的疗效评估，并提供新辅助化疗的临床评估程序。

关键字： 新辅助化疗，乳腺癌，反应评估