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Zeolites for theranostic applications.
Journal of Materials Chemistry B ( IF 7 ) Pub Date : 2020-06-30 , DOI: 10.1039/d0tb00719f
Mohsen Khodadadi Yazdi 1 , Payam Zarrintaj , Hadi Hosseiniamoli , Amin Hamed Mashhadzadeh , Mohammad Reza Saeb , Joshua D Ramsey , Mohammad Reza Ganjali , Masoud Mozafari
Affiliation  

Theranostic platforms bring about a revolution in disease management. During recent years, theranostic nanoparticles have been utilized for imaging and therapy simultaneously. Zeolites, because of their porous structure and tunable properties, which can be modified with various materials, can be used as a delivery agent. The porous structure of a zeolite enables it to be loaded and unloaded with various molecules such as therapeutic agents, photosensitizers, biological macromolecules, MRI contrast agents, radiopharmaceuticals, near-infrared (NIR) fluorophores, and microbubbles. Furthermore, theranostic zeolite nanocarriers can be further modified with targeting ligands, which is highly interesting for targeted cancer therapies.

中文翻译:

用于沸石的沸石。

Theranostic平台带来了疾病管理方面的一场革命。近年来,治疗治疗性纳米颗粒已被同时用于成像和治疗。沸石由于其多孔结构和可调节的特性,可以用各种材料改性,因此可以用作传递剂。沸石的多孔结构使其可以装载和卸载各种分子,例如治疗剂,光敏剂,生物大分子,MRI造影剂,放射性药物,近红外(NIR)荧光团和微泡。此外,可以用靶向配体进一步修饰治疗型沸石纳米载体,这对于靶向癌症治疗而言非常有趣。
更新日期:2020-07-22
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