Abstract

Sound and vibration have been shown to alter animal behavior and induce physiological changes as well as to cause effects at the cellular and molecular level. For these reasons, both environmental factors have a considerable potential to alter research outcomes when the outcome of the study is dependent on the animal existing in a normal or predictable biological state. Determining the specific levels of sound or vibration that will alter research is complex, as species will respond to different frequencies and have varying frequencies where they are most sensitive. In consideration of the potential of these factors to alter research, a thorough review of the literature and the conditions that likely exist in the research facility should occur specific to each research study. This review will summarize the fundamental physical properties of sound and vibration in relation to deriving maximal level standards, consider the sources of exposure, review the effects on animals, and discuss means by which the adverse effects of these factors can be mitigated.

中文翻译：

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声音和振动作为陆生脊椎动物模型中的研究变量。

摘要

声音和振动已被证明可以改变动物的行为并引起生理变化，并在细胞和分子水平上产生影响。由于这些原因，当研究结果依赖于以正常或可预测的生物学状态存在的动物时，这两种环境因素都有相当大的潜力来改变研究结果。确定将改变研究的特定声音或振动水平是复杂的，因为物种会对不同的频率做出反应，并且在它们最敏感的地方具有不同的频率。考虑到这些因素可能改变研究，应针对每项研究对文献和研究设施中可能存在的条件进行彻底审查。