For the fact that articular cartilage is a highly organized and avascular tissue, cartilage defects are limited to spontaneously heal, which would subsequently progress to osteoarthritis. Many methods have been developed to enhance the ability for cartilage regeneration, among which magnetically actuated manipulation has attracted interests due to its biocompatibility and non-invasive manipulation. Magnetically actuated manipulation that can be achieved by introducing magnetic nanoparticles and magnetic field. This review summarizes the cutting-edge research on the chondrogenic enhancements via magnetically actuated manipulation, including cell labeling, cell targeting, cell assembly, magnetic seeding and tissue engineering strategies.

对于关节软骨是高度组织化的无血管组织这一事实，软骨缺陷仅限于自发愈合，随后会发展为骨关节炎。已经开发了许多方法来增强软骨再生的能力，其中磁致动操纵由于其生物相容性和非侵入性操纵而引起了人们的兴趣。可以通过引入磁性纳米粒子和磁场来实现磁驱动操纵。这篇综述总结了通过磁致动操纵对软骨形成增强的最新研究，包括细胞标记，细胞靶向，细胞组装，磁性播种和组织工程策略。