In recent years, electrospun polymer fibers have gained attention for various antibacterial applications. In this work, the effect of positively charged polymer fiber mats as antibacterial gauze is studied using electrospun poly(caprolactone) and polyaniline nanofibers. Chloroxylenol, an established anti-microbial agent is used for the first time as a secondary dopant to polyaniline during the electrospinning process to make the surface of the polyaniline fiber positively charged. Both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli are used to investigate the antibacterial activity of the positively charged and uncharged polymer surfaces. The results surprisingly show that the polyaniline surface can inhibit the growth of both bacteria even when chloroxylenol is used below its minimum inhibitory concentration. This study provides new insights allowing the better understanding of dopant-based, intrinsically conducting polymer surfaces for use as antibacterial fiber mats.

近年来，静电纺聚合物纤维在各种抗菌应用中受到关注。在这项工作中，使用静电纺丝聚己内酯和聚苯胺纳米纤维研究了带正电的聚合物纤维垫作为抗菌纱布的效果。氯二甲酚是一种成熟的抗菌剂，首次在静电纺丝过程中用作聚苯胺的二次掺杂剂，使聚苯胺纤维表面带正电。革兰氏阳性金黄色葡萄球菌和革兰氏阴性大肠杆菌均用于研究带正电和不带电聚合物表面的抗菌活性。结果令人惊讶地表明，即使当使用低于其最小抑制浓度的氯二甲苯酚时，聚苯胺表面也能抑制两种细菌的​​生长。这项研究提供了新的见解，使人们能够更好地了解用作抗菌纤维垫的基于掺杂剂的本征导电聚合物表面。