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Flow dynamics of vitreous humour during saccadic eye movements.
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2020-06-30 , DOI: 10.1016/j.jmbbm.2020.103860
Andreia F Silva 1 , Francisco Pimenta 2 , Manuel A Alves 2 , Mónica S N Oliveira 3
Affiliation  

In this work, we reveal the flow dynamics of Vitreous Humour (VH) gel and liquid phases during saccadic movements of the eye, considering the biofluids viscoelastic character as well as realistic eye chamber geometry and taking into account the saccade profile. We quantify the differences in the flow dynamics of VH gel and liquid phases using viscoelastic rheological models that are able to model the VH shear rheology, considering different amplitudes of saccadic movements (10, 20, 30 and 40). For this purpose, the computational fluid dynamics (CFD) open source software OpenFOAM® was used. The results portray a distinct flow behaviour for the VH gel and liquid phases, with inertial effects being more significant for the VH liquid phase. Moreover, the Wall Shear Stress (WSS) values produced by the VH gel phase are more than twice of those generated by the VH liquid phase. Results also show that for different amplitudes of eye movement both the velocity magnitude in the vitreous cavity and the shear stresses on the cavity walls rise with increasing saccadic movement displacement.



中文翻译:

眼球震荡时玻璃体液的流动动力学。

在这项工作中,我们考虑到了生物流体的粘弹特性以及现实的眼腔几何形状并考虑了扫视轮廓,揭示了在眼睛的眼跳运动期间玻璃质幽默(VH)凝胶和液相的流动动力学。我们使用能够模拟VH剪切流变学的粘弹性流变模型来量化VH凝胶和液相流动动力学的差异,并考虑了相声运动的不同幅度(10∘20∘30∘40∘)。为此,使用了计算流体动力学(CFD)开源软件OpenFOAM®。结果显示出VH凝胶和液相具有明显的流动行为,而VH液相的惯性效应更为显着。此外,由VH凝胶相产生的壁切应力(WSS)值是由VH液相产生的壁切应力(WSS)值的两倍以上。结果还表明,对于不同幅度的眼动,玻璃体腔内的速度幅度和腔壁上的切应力都随着眼跳运动位移的增加而升高。

更新日期:2020-06-30
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