BACKGROUND:The consumption of fruits, mainly berries, has been associated with beneficial health properties. These properties would be related to the quantity and quality of the metabolites present. Some native berries from the Andes, such as Andean elderberry, would be an important source of metabolites with bioactive properties. OBJECTIVES:To evaluate at the physico-chemical and metabolomic level the characteristics of the elderberry from four different high Andean regions, and to determine their bioactive potential through in vitro tests. RESULTS:Significant differences were found in the evaluated characteristics according to the Region of procedence of the fruit. Glucose was the main sugar for all berry samples, followed by fructose. Among the most important organic acids, citric and malic acid were found. Elderberry from Apurímac presented the highest content of total sugars and lower content of total acids in comparison to the samples from other procedences. UPLC-PDA results indicate that Junín elderberries presented the highest value of total phenolic compounds with high contents of flavonols, hydroxycinnamic acids and anthocyanins. Andean elderberry presented cyanidin 3-O-glucoside and cyanidin 3-O-sambubioside as main anthocyanins as well as their respective isomers. All samples showed inhibition activities against the different evaluated enzymes. Elderberries from Apurímac and Junín, displayed the lowest values of IC50 for the inhibition of α-amylase and α-glucosidase, while for the inhibition of lipase and angiotensin converting enzyme (ACE-I) elderberries from Junín displayed the lowest IC50 values. CONCLUSIONS:The results of this study suggest that Andean elderberry could be considered as an important source of bioactive compounds with properties that could be highlighted by the nutraceutical and functional food industries.

中文翻译：

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安第斯接骨木接骨木（Sambucus nigra subsp。peruviana）的理化特性，代谢组学特征和体外抗氧化剂，抗高血压，抗肥胖和抗糖尿病特性

背景：食用水果（主要是浆果）与有益健康的特性有关。这些性质将与存在的代谢物的数量和质量有关。一些来自安第斯山脉的本地浆果，例如安第斯接骨木浆果，将是具有生物活性的代谢产物的重要来源。目的：在理化和代谢组学水平上评估来自四个安第斯山高地区的接骨木的特性，并通过体外试验确定其生物活性潜力。结果：根据水果的加工区域，评价特征存在显着差异。葡萄糖是所有浆果样品中的主要糖，其次是果糖。在最重要的有机酸中，发现了柠檬酸和苹果酸。与其他程序的样品相比，来自Apurímac的接骨木浆果的总糖含量最高，而总酸的含量较低。UPLC-PDA结果表明，胡宁接骨木的总酚类化合物含量最高，其中黄酮醇，羟肉桂酸和花色苷含量高。安第斯接骨木浆果提出了花青素3-O-葡糖苷和花青素3-O-sambubiobioside作为主要花色苷及其各自的异构体。所有样品均显示出对不同评估酶的抑制活性。来自Apurímac和Junín的接骨木莓对α-淀粉酶和α-葡萄糖苷酶的抑制作用表现出最低的IC50值，而对于抑制脂肪酶和血管紧张素转化酶（ACE-I）的抑制作用，来自Junín的接骨木浆果表现出最低的IC50值。结论：