The current article aims to synthesize some new arylazo-thiophenes for dyeing polyester fabrics and screen their antimicrobial activities. The new 4-arylazo-2-(N-pyrazolylcarboxamido)-thiophene dyes 4a–e were prepared by the reaction of 2-acetyl-2-arylazo-thioacetanilide derivative 1 with 2-chloro-N-(3-methyl-1H-pyrazol-5-yl)acetamide derivative 2. The structures of these prepared analogues were established via Fourier-transform infrared and 1H/13C nuclear magnetic resonance spectra. The synthesized dyestuffs were applied to polyester fabrics after establishing the optimal dyeing conditions at 130 ºC, high pressure, 3% shade, and liquor ratio 20:1 at pH 5. Furthermore, the dyed fabrics obtained under these optimal conditions resulted in proper colorfastness toward washing, rubbing, sublimation and perspiration, and were adequate for light fastness. They showed respectable antibacterial effectiveness against two bacterial strains, Staphylococcus aureus (Gram-positive) and Salmonella typhimurium (Gram-negative) bacteria. The dyed fabric with dye 4d displayed the best antibacterial activities with percentage reduction of 88% and 76% against S. aureus and S. typhimurium bacteria, respectively.

中文翻译：

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4-芳基偶氮-2-(N-吡唑基甲酰胺基)噻吩分散染料用于涤纶染色的合成及抗菌评价

本文旨在合成一些用于涤纶织物染色的新型芳基并噻吩并筛选其抗菌活性。新的 4-芳基-2-(N-吡唑基甲酰胺基)-噻吩染料 4a-e 是通过 2-乙酰基-2-芳基-硫代乙酰苯胺衍生物 1 与 2-氯-N-(3-甲基-1H- pyrazol-5-yl) 乙酰胺衍生物 2. 这些制备的类似物的结构是通过傅里叶变换红外光谱和 1H/13C 核磁共振光谱建立的。在 130 ºC、高压、3% 色光和浴比 20:1、pH 5 下建立最佳染色条件后，将合成染料应用于涤纶织物。此外，在这些最佳条件下获得的染色织物对耐水洗、摩擦、升华、排汗，耐光牢度足够。它们对两种细菌菌株，金黄色葡萄球菌（革兰氏阳性）和鼠伤寒沙门氏菌（革兰氏阴性）细菌显示出可观的抗菌效果。用染料 4d 染色的织物显示出最好的抗菌活性，对金黄色葡萄球菌和鼠伤寒沙门氏菌的抗菌活性分别降低了 88% 和 76%。