Despite the importance of P-chiral organophosphorus compounds in asymmetric catalysis, transition metal-catalyzed methods for accessing P-chiral phosphine derivatives are still limited. Herein, a catalytic enantioselective method for the synthesis of P-stereogenic alkenylphosphinates is developed through asymmetric hydrophosphorylation of alkynes. This process is demonstrated for a wide range of racemic phosphinates and leads to diverse P-stereogenic alkenylphosphinates directly.

中文翻译：

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钯催化的炔烃不对称氢磷酸化：轻松获得 P-立体次膦酸盐

尽管P-手性有机磷化合物在不对称催化中很重要，但过渡金属催化的获取P-手性膦衍生物的方法仍然有限。在此，通过炔烃的不对称氢磷酸化开发了一种催化对映选择性合成P-立体烯基次膦酸盐的方法。该过程已针对多种外消旋次膦酸盐得到证实，并直接产生多种P-立体烯基次膦酸盐。