During the last three decades or so, many efforts have been made to study the protein cleavage sites by some disease-causing enzyme, such as HIV (human immunodeficiency virus) protease and SARS (severe acute respiratory syndrome) coronavirus main proteinase It has become increasingly clear via this mini-review that the motivation driving the aforementioned studies is quite wise, and that the results acquired through these studies are very rewarding, particularly for developing peptide drugs

中文翻译：

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扭曲的关键理论及其对药物开发的启示

在过去的三十年左右的时间里，人们做了很多努力来研究某些致病酶的蛋白质裂解位点，例如 HIV（人类免疫缺陷病毒）蛋白酶和 SARS（严重急性呼吸系统综合症）冠状病毒主要蛋白酶。通过这篇小型评论清楚地表明，推动上述研究的动机是非常明智的，并且通过这些研究获得的结果非常有益，特别是对于开发肽药物