We herein report an iridium-catalyzed enantioselective α-C(sp3)-H borylation of a wide range of azacycles. The combination of an iridium precursor and a chiral bidentate boryl ligand has shown effectively differentiating enantiotropic methylene C-H bonds from a single carbon center, affording a variety of synthetically useful cyclic amines from readily available starting materials with good to excellent enantioselectivities.

中文翻译：

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铱催化的氮杂环的对映选择性α-C(sp3)-H硼酸化

我们在此报告了铱催化的多种氮杂环的对映选择性 α-C(sp3)-H 硼酸化。铱前体和手性双齿硼基配体的组合已显示有效区分对映亚甲基 CH 键与单个碳中心，从易于获得的起始材料中提供各种合成有用的环胺，具有良好到出色的对映选择性。