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TNF‐α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury
Cell Proliferation ( IF 8.5 ) Pub Date : 2020-05-17 , DOI: 10.1111/cpr.12829
Yao Wang 1 , Haiyue Zhang 1 , Qian Chen 1 , Fangzhou Jiao 1 , Chunxia Shi 1 , Maohua Pei 1 , Jian Lv 2 , Hong Zhang 2 , Luwen Wang 1 , Zuojiong Gong 1
Affiliation  

Acute kidney injury (AKI) is a common complication of acute liver failure (ALF). Pyroptosis is a necrosis type related to inflammation. This study aimed to investigate the role of TNF‐α/HMGB1 pathway in pyroptosis during ALF and AKI.

中文翻译:

TNF-α/HMGB1 炎症信号通路调节肝功能衰竭和急性肾损伤期间的细胞焦亡

急性肾损伤 (AKI) 是急性肝功能衰竭 (ALF) 的常见并发症。焦亡是一种与炎症有关的坏死类型。本研究旨在探讨 TNF-α/HMGB1 通路在 ALF 和 AKI 期间细胞焦亡中的作用。
更新日期:2020-05-17
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