当前位置: X-MOL 学术Eur. J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Front Cover: Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation (Eur. J. Org. Chem. 25/2020)
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-06-29 , DOI: 10.1002/ejoc.202000882
Praveen K. Chinthakindi 1 , Andrea Benediktsdottir 1 , Per I. Arvidsson 2, 3 , Yantao Chen 4 , Anja Sandström 1
Affiliation  

The Front Cover shows the combined world of solid‐phase peptide synthesis and sulfur chemistry on a background of a sulfur landscape. A peptide chain attached to a polymer resin is functionalized through formation of a sulfonamide and the magic touch of triphenylphosphine dichloride. The resulting sulfonimidamide pseudopeptides are thereafter released from the resin. The method allows easy generation of novel chemical libraries, useful in drug discovery. Graphic design by Andrea Benediktsdottir. More information can be found in the Full Paper by P. K. Chinthakindi, A Benediktsdottir, A. Sandström et al.
image


中文翻译:

封面:磺酰亚胺酰胺类伪肽的固相合成和文库生成(Eur。J. Org。Chem。25/2020)

封面以硫素为背景,展示了固相肽合成和硫化学的结合世界。连接到聚合物树脂上的肽链通过磺酰胺的形成和三苯基膦二氯化物的神奇触感而功能化。此后,将所得的磺酰亚胺酰胺酰胺假肽从树脂中释放出来。该方法可以轻松生成可用于药物发现的新型化学文库。图形设计由Andrea Benediktsdottir设计。有关更多信息,请参见P. K. Chinthakindi,A Benediktsdottir,A。Sandström等人的论文全文。
图片
更新日期:2020-07-01
down
wechat
bug