Many fungal metabolites are salicylaldehyde containing polyketide natural products and are often isolated from the fungus culture broth. These metabolites commonly exhibit phytotoxicity, however, some compounds exerted other biological activities including immunosuppressive activity. We have developed a unified synthetic strategy that provides easy access to ent-pyriculol, ent-epipyriculol, ent-dihydropyriculol, ent-epidihydropyriculol, sordariol, sordarial, 12-methoxy sordariol and agropyrenol.

中文翻译：

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统一的方法来含有聚酮化合物的水杨醛的天然产物：全合成耳鼻喉科-pyriculol，耳鼻喉科-epipyriculol，耳鼻喉科-dihydropyriculol，耳鼻喉科-epidihydropyriculol，sordariol，sordarial，12-甲氧sordariol，和agropyrenol

许多真菌代谢产物是含有水杨醛的聚酮化合物天然产物，通常从真菌培养液中分离出来。这些代谢物通常表现出植物毒性，但是，某些化合物具有其他生物活性，包括免疫抑制活性。我们已经制定了统一的综合战略，提供方便耳鼻喉科-pyriculol，耳鼻喉科-epipyriculol，耳鼻喉科-dihydropyriculol，耳鼻喉科-epidihydropyriculol，sordariol，sordarial，12-甲氧sordariol和agropyrenol。