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Facile preparation of cesium salt of tungstophosphoric acid for catalytic synthesis of one-pot two-component 1,3,4-oxadiazole derivatives in water: A doubly green approach
Sustainable Chemistry and Pharmacy ( IF 6 ) Pub Date : 2020-06-29 , DOI: 10.1016/j.scp.2020.100279
Mshari A. Alotaibi , Md Afroz Bakht , Abdulrahman I. Alharthi , Mohammed H. Geesi , Mohammed B. Alshammari , Yassine Riadi

Solid acid catalysts facilitate many organic reactions, Cesium salt of tungstophosphoric acid (CsPW) exhibits excellent catalytic activity due to its safety, efficiency, strong acidity, cost-effectiveness and being water tolerant. CsPW has provided promising results under aqueous conditions with the high catalytic efficiency for the synthesis of target 1,3,4-oxadiazoles. The prepared catalyst was fully characterized by FT-IR, X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET), scanning electron microscopy (SEM), Energy-dispersive X-ray spectroscopy (EDAX) and X-ray photoelectron spectroscopy (XPS). 1,3,4-oxadiazoles synthesis is an environmentally friendly, clean and safe synthetic process in short reaction time, simple workup, excellent yield and catalytic recovery. The best yield results (94%) were obtained using cesium tungstophosphoric acid catalyst by model compound in just 40 min. In addition, thermodynamic and kinetic model reaction analysis was also conducted at a temperature range of 298–323 K under the influence of the catalyst. The reaction under kinetic analysis was found to be more regulated than thermodynamic, which may be attributed to the influence of the optimum amount of catalyst being used.



中文翻译:

钨磷酸铯盐的简便制备,用于在水中催化合成一锅两组分1,3,4-恶二唑衍生物:双绿色方法

固体酸催化剂促进许多有机反应,钨磷酸铯盐(CsPW)由于其安全性,效率,强酸度,成本效益和耐水性而显示出优异的催化活性。CsPW在水性条件下以高催化效率合成目标1,3,4-恶二唑提供了令人鼓舞的结果。FT-IR,X射线衍射(XRD),Brunauer-Emmett-Teller(BET),扫描电子显微镜(SEM),能量色散X射线光谱仪(EDAX)和X射线光电子光谱仪(XPS)。1,3,4-恶二唑合成是一种环境友好,清洁安全的合成方法,反应时间短,后处理简单,收率高,催化回收率高。使用钨磷铯铯催化剂通过模型化合物在短短40分钟内可获得最佳收率结果(94%)。此外,在催化剂的影响下,还在298–323 K的温度范围内进行了热力学和动力学模型反应分析。发现动力学分析下的反应比热力学更受调控,这可能归因于所用催化剂的最佳量的影响。

更新日期:2020-06-29
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