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Formation of Nanostructures on Magnesium alloy by Anodization for Potential Biomedical Applications
Materials Today Communications ( IF 3.8 ) Pub Date : 2020-06-29 , DOI: 10.1016/j.mtcomm.2020.101403
L Mohan 1, 2 , Srabani Kar 3 , B Nandhini 1 , Sathish Sundar Dhilip Kumar 4 , Moeto Nagai 2 , Tuhin Subhra Santra 1
Affiliation  

In the present work, we have investigated the formation of nanostructures on AZ31 magnesium alloy using electrochemical anodization technique. The formed nanostructures were efficiently showed bone-like apatite formation followed by its gradual increase, when immersed in simulated body fluid (SBF) and it exhibited controlled degradation in 7 days. Cell viability study was performed using MG-63 cells (human osteosarcoma cell lines) and revealed that the nanostructured surface has excellent biocompatibility by enhancing both cell adhesion and cell growth. The detailed characterization of this anodized surface was evaluated by field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray spectroscopy (EDS). Furthermore, surface-corrosion before and after anodization was examined by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization studies in SBF. The in-depth studies bring out the fact that native oxide in the sample is converted to a biocompatible nanostructure, which is created due to anodization in a particular electrolyte solution containing ethylene glycol and hybrid hydrofluoric acid mixture.



中文翻译:

阳极氧化在镁合金上形成纳米结构的潜在生物医学应用

在目前的工作中,我们已经研究了使用电化学阳极氧化技术在AZ31镁合金上形成纳米结构。当浸入模拟体液(SBF)中时,形成的纳米结构有效地显示出骨状磷灰石的形成,随后逐渐增加,并在7天内表现出受控的降解。使用MG-63细胞(人骨肉瘤细胞系)进行了细胞活力研究,结果表明,纳米结构表面通过增强细胞粘附力和细胞生长而具有出色的生物相容性。通过场发射扫描电子显微镜(FESEM)和能量色散X射线光谱(EDS)评估了该阳极氧化表面的详细特征。此外,通过电化学阻抗谱(EIS)和SBF中的电位动力极化研究检查了阳极氧化前后的表面腐蚀情况。深入的研究表明,样品中的天然氧化物被转化为生物相容性纳米结构,这是由于在包含乙二醇和氢氟酸混合液的特定电解质溶液中进行阳极氧化而产生的。

更新日期:2020-06-29
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